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Article: Ca[superscript]2+ response to ATP is due to release through Na[superscript]+-Ca[superscript]2+ exchangers.
- Article from:
- Science Letter
- Article date:
- September 21, 2004
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2004 SEP 21 - (NewsRx.com & NewsRx.net) -- The involvement of mitochondrial Na[superscript]+-Ca2+ exchange in intracellular Ca2+ increase induced by ATP in PC12 cells was the focus of a rexcent study.
"The involvement of mitochondrial Na[superscript]+-Ca[superscript]2+ exchange in Ca[superscript]2+ responses to ATP was examined in rat pheochromocytoma (PC) 12 cells. Intracellular Ca[superscript]2+ ([Ca[superscript]2+][subscript]i) and Na[superscript]+ concentrations ([Na[superscript]+][subscript]i) were measured using fura-2 and SBFI, respectively. ATP caused concentration-dependent increases in [Ca[superscript]2+][subscript]i and [Na[superscript]+[subscript]i," ...