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Article: DHEA: an alternative to estrogen-replacement therapy?(Literature Review & Commentary)(dehydroepiandrosterone)
- Article from:
- Townsend Letter for Doctors and Patients
- Article date:
- October 1, 2004
- Author:
CopyrightCOPYRIGHT 2004 The Townsend Letter Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Twenty postmenopausal women (aged 50-65 years) received 25 mg/day of dehydroepiandrosterone (DHEA) orally for 12 months. The mean serum concentrations of testosterone, estrone, and estradiol increased significantly and progressively, each reaching a 3- to 4- fold increase after 12 months. The mean serum concentration of progesterone increased significantly after 6 months, reaching a maximum increase of approximately 2.5-fold after 12 months. The mean concentration of growth hormone also increased significantly and progressively, reaching a maximum increase of more than 2-fold after 12 months. Plasma levels of luteinizing hormone and follicle-stimulating hormone decreased ...