Article: Integrative orthopedics and vitamin D: testing, administration, and new relevance in the treatment of musculoskeletal pain.

Introduction

While we are all familiar with the importance of vitamin D in calcium absorption and bone metabolism, many doctors and patients are not aware of the recent research on vitamin D and the widening range of therapeutic applications available for cholecalciferol, which can be classified as both a vitamin and a pro-hormone. (1) Additionally, we also now realize that the previously defined upper limit of safe intake at approximately 800 IU/day was set far too low and that the physiologic requirement for vitamin D may be as high as 5,000 IU/day, which is approximately half of the >10,000 IU that can be produced endogenously with full-body sun exposure. ...

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