Article: Cypress' ``Pain Assessment in Patients with Fibromyalgia Syndrome: A Consideration of Methods for Clinical Trials'' Published in Clinical Journal of Pain.

SAN DIEGO -- Electronic Diaries Demonstrate Improved Patient Compliance When Used in Fibromyalgia Clinical Trials

Cypress Bioscience, Inc. (Nasdaq:CYPB) announced today that a publication of a study in the Clinical Journal of Pain showed that, in clinical trials, pain assessment methods relying on recall could contribute to an apparent improvement in pain over time in the absence of a true therapeutic effect; such a methodological characteristic would constitute a component of a placebo response. Future clinical trials should consider using a real-time approach to pain assessment, which in this study appeared to mitigate against elevated baseline pain scores. In ...

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