Article: Telomere length predicts neutrophil recovery in G-CSF absence after ASCT.

2004 NOV 1 - (NewsRx.com & NewsRx.net) -- Telomere length predicts neutrophil recovery in G-CSF absence after peripheral blood autologous stem cell transplant.

"Hemopoietic regeneration after autologous peripheral blood progenitor cell (PBPC) trans plantation can be delayed in some patients despite adequate infusion of CD34+ cells. This suggests variability in the proliferation potential of the implanted cells, a capacity that may be predicted by their telomere length.

"To test this theory, telomere length was measured on stored apheresis samples from 36 patients aged 46.6[+ or -]11.1 years, who had undergone successful autologous PBPC transplantation ...

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