Article: The malaria parasite: change and conquer. (attack strategies of parasites)

A parasitic relationship resembles a biological arms race. Over evolutionary time, an infected host puts up a new defense to stave off a parasite, only to have that parasite evade the defense and sharpen its skills for circumventing the host's next defensive strategy. And so on, and so on, in a biochemical escalation process that usually ends with the parasite attaining the upper hand.

This change-and-conquer strategy has made it particularly difficult for scientists to develop vaccines against parasites, including the most dangerous malaria organism, Plasmodium falciparum (SN: 5/4/91, p.276). Now, researchers led by David J. Roberts of John Radcliffe Hospital ...

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