|
|
Article: P110 delta a key player in the allergic response.
- Article from:
- Health & Medicine Week
- Article date:
- November 8, 2004
CopyrightCOPYRIGHT 2004 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
|
2004 NOV 8 - (NewsRx.com & NewsRx.net) -- The suffering of millions of people with allergies could one day be eased, thanks to new research from U.K. investigators.
Findings from the University College London Branch of the Ludwig Institute for Cancer Research (LICR), published in Nature, detailed how inactivating a key signaling molecule called p110delta reduced the effect of allergies on mice.
Dr. Bart Vanhaesebroeck and his team at LICR, together with collaborators from Novartis Respiratory Disease Center headed by Dr. Peter Finan, found that inactivating p110delta in mast cells substantially reduces the allergic response seen in mice. In mice lacking ...