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Article: Antiangiogenic protein fragments harbor amyloid characteristics.
- Article from:
- Angiogenesis Weekly
- Article date:
- November 26, 2004
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2004 NOV 26 - (NewsRx.com & NewsRx.net) -- Antiangiogenic protein fragments harbor amyloid characteristics.
According to recent research published in the journal Blood, "tumor growth requires proteolytic activity. As a consequence, protein breakdown products are present in the circulation of patients with cancer. Within the past decade a large number of proteolytic fragments have been identified that inhibit angiogenesis and tumor growth."
"The mechanism of action of these inhibitors is still poorly understood. We recently found that the effects of the angiogenesis inhibitor endostatin on endothelial cells is critically dependent on the presence of ...