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Article: Antioxidant vitamins can reverse DEHP-induced murine sperm disruption.
- Article from:
- Biotech Week
- Article date:
- November 24, 2004
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2004 NOV 24 - (NewsRx.com & NewsRx.net) -- Sperm disruption induced by di-(2-ethylhexyl) phthalate (DEHP) can be reversed with antioxidant vitamins in mice.
DEHP, "now regarded as an endocrine disruptor, can experimentally induce spermatogenic disturbance in laboratory animals," scientists in Japan explained.
"Our previous study demonstrated that antioxidant vitamins (vitamins C and E) supplementation during DEHP treatment significantly protected the rat seminiferous epithelium from DEHP gonadotoxicity," noted M. Ablake and coauthors at the Tokyo Medical University. In the subsequent study, they "gave these antioxidant vitamins to mice already having ...