Article: Leptin inhibits norepinephrine efflux from the hypothalamus in vitro.

2004 DEC 6 - (NewsRx.com & NewsRx.net) -- Leptin inhibits norepinephrine efflux from the hypothalamus in vitro.

According to recent research published in the journal Brain Research, "Leptin, a hormone secreted by adipocytes, produces a number of central and neuroendocrine effects, the mechanisms behind which are not completely understood. Hypothalamic norepinephrine (NE) is involved in many of the neuroendocrine effects that are associated with leptin. Therefore, we hypothesized that leptin could affect hypothalamic NE activity to bring about its central and neuroendocrine effects."

"Because gamma aminobutyric acid (GABA) is known to affect the release ...

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