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Article: RhoA inactivation potentiates axon regeneration.
- Article from:
- Science Letter
- Article date:
- December 7, 2004
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2004 DEC 7 - (NewsRx.com & NewsRx.net) -- RhoA inactivation potentiates axon regeneration.
According to recent research published in the Journal of Neuroscience, "the inability of mature central nervous system (CNS) neurons to regenerate injured axons has been attributed to a loss of inherent growth potential of cells and to inhibitory signals associated with myelin and the glial scar."
"The present study investigated two complementary issues: (1) whether mature CNS neurons can be stimulated to alter their gene expression profile and switch into a strong growth state; and (2) whether inactivating RhoA, a convergence point for multiple inhibitory ...