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Article: Studies on the aqueous extract of Terminalia chebula as a potent antioxidant and a probable radioprotector.
- Article from:
- Phytomedicine: International Journal of Phytotherapy & Phytopharmacology
- Article date:
- September 1, 2004
- Author:
CopyrightCOPYRIGHT 2004 Urban & Fischer Verlag. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Abstract
Aqueous extract of a natural herb, Terminalia chebula was tested for potential antioxidant activity by examining its ability to inhibit [gamma]-radiation-induced lipid peroxidation in rat liver microsomes and damage to superoxide dismutase enzyme in rat liver mitochondria. The antimutagenic activity of the extract has been examined by following the inhibition of [gamma]-radiation-induced strand breaks formation in plasmid pBR322 DNA. In order to understand the phytochemicals responsible for this, HPLC analysis of the extract was carried out, which showed the presence of compounds such as ascorbate, gallic acid and ellagic acid. This was also confirmed by ...