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Article: IGF-1 may help some children with short stature.(Metabolic Disorders)
- Article from:
- Family Practice News
- Article date:
- February 15, 2005
- Author:
CopyrightCOPYRIGHT 2005 International Medical News Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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LISBON -- Primary insulin-like growth factor deficiency is one and a half times more common than growth hormone deficiency among children with short stature and a deficiency of insulin-like growth factor-1, George M. Bright, M.D., reported at the 12th International Congress of Endocrinology.
Both deficiency groups have low levels of insulin-like growth factor-1 (IGF-1), and the two groups cannot be distinguished clinically. But the difference is important, because children with primary insulin-like growth factor deficiency-1 (IGFD) are often insensitive to growth hormone (GH) therapy and may respond better to IGF-1 replacement, said Dr. Bright, vice president of ...