|
|
Article: The oxygen view of osteoporosis: bone homeostasis is but one face of oxygen homeostasis.(Oxygen Homeostasis)
- Article from:
- Townsend Letter for Doctors and Patients
- Article date:
- April 1, 2005
- Author:
CopyrightCOPYRIGHT 2005 The Townsend Letter Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
|
The human anatomy and physiology evolved under the organizing influence of oxygen. (1-4) Accordingly, oxygen not only provides signaling for all developmental, differentiative, and dying processes, it also serves as the principal nutrient for the body. Viewed in that light, bone homeostasis is but one face of oxygen homeostasis. Based on those considerations, I recently put forth the Oxygen Model of osteoporosis that recognizes disturbances of oxygen homeostasis in the bone tissue as the fundamental energetic-molecular events that lead to bone loss clinically designated as osteopenia and osteoporosis. (5)
[ILLUSTRATION OMITTED]
In the prevailing model of ...