Article: VaxGen Reports Positive Results of Animal Efficacy Studies of Smallpox Vaccine Candidate.

VaxGen, Inc. today announced top-line results from two animal studies of the effectiveness of its attenuated smallpox vaccine candidate, LC16m8. Both studies, which were conducted in mice and rabbits, respectively, demonstrated that a single dose of LC16m8 was as effective as the currently licensed vaccine, DryVax, in protecting against a lethal poxvirus challenge. LC16m8 is a live attenuated vaccinia vaccine and has been licensed for use in humans in Japan since 1980.

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"These are the first animal efficacy studies to be reported which directly compare the effectiveness of LC16m8 and ...

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