Article: Adolor Corporation Announces Positive Top-Line Results in 2nd Phase 3 Study of Alvimopan in Postoperative Ileus; - Primary Endpoint Statistically Significant in 6 mg and 12 mg Doses - - Conference Call and Webcast at 8:45 a.m. EDT on September 23, 2003 -.

Adolor Corporation announced today top-line results of its second Phase 3 clinical study (14CL313) of Entereg(TM) (alvimopan) in the management of postoperative ileus (POI). A statistically significant difference was achieved in the primary endpoint of the study, time to recovery of gastrointestinal function, in the Entereg(TM) (alvimopan) 6 mg and 12 mg treatment groups when each is compared to the placebo group.

"We are very excited to report today's positive results in both the 6 mg and 12 mg treatment groups, and believe they support our goal of submitting a New Drug Application for Entereg(TM) (alvimopan) to the U.S. Food and Drug Administration late in ...

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