Article: Rigel Initiates Multi-Dose Safety Trial of R112 for Allergic Rhinitis; Trial Designed to Establish Safety of R112 for Longer-Term Use.

Rigel Pharmaceuticals, Inc. today announced that it has initiated a multi-dose safety trial of R112, an experimental drug to treat allergic rhinitis. The goal of this trial is to establish the longer-term, multi-dose safety of R112 in various dosing regimens. Results of this trial are expected by January 2004 and will allow Rigel to enter into broader, longer-term, multi-dose efficacy trials in the first half of 2004.

In late July, Rigel released the results of a Phase I/II study which evaluated the efficacy and safety of a single intra-nasal administration of R112 in volunteers with asymptomatic seasonal allergic rhinitis. The study demonstrated significant ...

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