Article: Sepracor Submits U.S. New Drug Application for ESTORRA(TM) Brand Eszopiclone for Treatment of Insomnia.

Sepracor Inc. today announced that it has submitted a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) seeking clearance to market ESTORRA(TM) brand eszopiclone 2 mg and 3 mg tablets for the treatment of transient and chronic insomnia. ESTORRA was studied in the 3 mg dosage strength for adults and in the 2 mg dosage strength for treatment of the elderly population.

The NDA contains a total of 24 clinical trials, which included more than 2,700 adult and elderly subjects, and more than 60 preclinical studies. A total of six randomized, placebo-controlled Phase III studies, including one with a positive control, were conducted for the ...

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