Article: Development and evaluation of a sickle cell disease assessment instrument.(Continuing Education Series)

Only recently has the ability to identify very young children at high risk for severe sickle cell disease complications been reported (Miller et al., 2000). Early identification combined with recent advances in treatment, such as hydroxyurea therapy and bone marrow transplant, could potentially prevent predicted adverse outcomes (Walters et al., 1996; Charache et al., 1995). Yet no assessment instrument has been developed and evaluated to identify these young children.

The purpose of this study was twofold: (a) to develop a Sickle Cell Disease Assessment Instrument that includes two domains--high-risk identification and disease severity classification--and (b) to ...

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