Article: Somaxon Pharmaceuticals Announces Positive Results in a Phase II Dose-Finding Study of Low-Dose Doxepin in Elderly Patients with Primary Sleep Maintenance Insomnia.

SAN DIEGO -- Somaxon Pharmaceuticals Inc., a specialty pharmaceutical company focused on developing and marketing products for the treatment of neuro-psychiatric disorders, today announced that low-dose doxepin demonstrated statistically significant results in a Phase II dose-finding study in elderly patients with primary sleep maintenance insomnia. Low-dose doxepin demonstrated efficacy in its primary endpoint, Wake Time During Sleep (WTDS) at all doses studied, 1 mg, 3 mg and 6 mg. Low-dose doxepin also demonstrated efficacy in all secondary sleep maintenance endpoints as well as patient reported outcomes. In all dose groups, there were no differences in adverse events ...

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