Article: T cells implicated in RA patients with lung disease.(Musculoskeletal Disorders)(Rheumatoid arthritis )

Rheumatoid arthritis patients suffering from interstitial lung disease may eventually have more targeted therapies, thanks to new evidence on the patho-physiology of the pulmonary condition.

Using computer-assisted image analysis, a team of investigators from the Mayo Clinic in Rochester, Minn., demonstrated an increased number of certain subtypes of T cells in the lung tissue of rheumatoid arthritis (RA) patients with interstitial pneumonitis (IP) compared with patients with the same pulmonary diagnosis who did not have RA.

The results support the long-held hypothesis that lung disease associated with RA might be T-cell driven, said Eric Matteson, M.D., ...

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