Article: Rigel Begins U.S. Clinical Testing of Allergy Drug.

Efficacy Data Expected to be Available Mid-Year

Rigel Pharmaceuticals, Inc. has initiated clinical testing in the United States for the company's first product, a drug to treat allergic rhinitis.

The experimental compound, R112, is the first of a new class of drug directed at immune blood cells called mast cells. Activation of these cells is one of the earliest steps in the initiation of an inflammatory response in allergy and asthma.

"Rigel's investigational drug represents a novel approach for intervening in the allergic process," said Harold S. Nelson, M.D., the study's lead investigator and professor of medicine at National Jewish Medical ...

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