Article: Inspire Pharmaceuticals Announces Initiation of Phase III Trial in Perennial Allergic Rhinitis.

Inspire Pharmaceuticals, Inc. today announced the initiation of a Phase III clinical trial of INS37217 Intranasal in patients with perennial allergic rhinitis (PAR). The trial is a randomized, parallel-group, double-blind study designed to evaluate the safety and efficacy of INS37217 Intranasal in a 10mg/ml non-preserved nasal spray formulation, compared to placebo. This dose was selected based on efficacy results from Phase I and II studies of INS37217 Intranasal in which the 10mg/ml dose consistently demonstrated the most robust effect. The 28-day Phase III study will be conducted in approximately 630 patients at 24 centers across the United States. The primary ...

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