Article: A single dose of ibuprofen or acetaminophen: which is most effective?

Which do you think is more effective for relieving your child's pain or fever, acetaminophen (e.g., Tylenol) or ibuprofen (e.g., Advil)? Which is safer? Although these drugs are the most frequently used over-the-counter medications for treating children's pain and fever, it turns out that even the experts disagree.

We used a special statistical technique called "meta-analysis" to help resolve this disagreement. It involves mathematically combining the data from all available high quality studies addressing a particular research question, and then reanalyzing the data as though they were from one very large study conducted at different times and places. We can ...

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