Article: Sibutramine may help children with hypothalmic disorders lose weight.(Metabolic Disorders)

Las Vegas -- Sibutramine (Meridia), an adult diet drug, can help control the weight of children with hypothalamic obesity and other syndromes that make behavioral interventions ineffective, results from a small, double-blind, placebo-controlled trial suggest.

Claude Marcus, M.D., reported statistically significant differences in reduction of body mass index (BMI) when the children were on sibutramine, compared with when they were on placebo. Triglyceride levels also declined significantly with sibutramine, Dr. Marcus said at the annual meeting of the North American Association for the Study of Obesity.

"These are very difficult patients to treat," ...

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