Article: Hismanal should not be taken with certain other drugs. (antihistamine drug)

People who take the non-sedating prescription antihistamine Hismanal (astemizole) should not take certain antifungal or antibiotic drugs at the same time because of the risk of life-threatening cardiac arrhythmias, commonly known as abnormal heart rhythms. This is the second non-sedating prescription antihistamine found to have tiffs potential drug interaction problem.

Hismanal is prescribed to treat seasonal allergies and hives.

Last October, FDA asked Janssen Pharmaceutica, manufacturer of Hismanal, to warn physicians and other health professionals not to prescribe the antibiotic erythromycin or the anti-fungals Nizoral (ketoconazole) or Sporanox ...

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