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Article: Epigallocatechin gallate (EGCG) (TEAVIGO[TM]) does not impair nonhaem-iron absorption in man.
- Article from:
- Phytomedicine: International Journal of Phytotherapy & Phytopharmacology
- Article date:
- June 1, 2005
- Author:
CopyrightCOPYRIGHT 2005 Urban & Fischer Verlag. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Abstract
A number of studies have shown that tea catechins can inhibit intestinal iron absorption, mostly iron in the nonhaem form. This randomized, double-blind, placebo-controlled, 3-periods cross-over study examined the degree of inhibition of nonhaem iron absorption by pure crystalline epigallocatechin gallate (EGCG). The study was designed to show the maximum inhibitory action of EGCG by selecting 30 healthy women with low iron stores. Treatments were 150 mg, 300 mg EGCG and placebo each for 8 consecutive study days with a wash-out period of 14 days between treatments. Iron incorporation was assessed by supplying [.sup.57]Fe orally and [.sup.58]Fe ...