Article: The symptoms, neurobiology, and current pharmacological treatment of depression.

Abstract: Depression as a medical disorder increasingly is being recognized and treated. The mood of an individual with major depression is often described as sad, hopeless, or discouraged, and there are many physical symptoms associated with depression. Pharmacologic treatments for depression have advanced greatly since the development of the first therapies, monoamine oxidase inhibitors (MAOIs). Many medications, such as tricyclic antidepressants (TCAs), selective seroton& reuptake inhibitors (SSRIs), and serotonin norepinephrine reuptakz, inhibitors (SNRIs), currently are available to help combat &is health problem. Newer medications have eliminated many of the side ...

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