Article: In Silico Techniques Tell How the Protein Turns.

By Elizabeth Tolchin, Reed Life Science News Editor

Computational methods that can predict the structure of a protein from its amino acid sequence are improving. Developers of such programs say that the technology may one day completely supplant experimental structure determination.

The biological function of a protein is dependent on the protein folding into the correct structure. Predicting the structure of a protein from its amino acid sequence was once considered a distant goal. For this reason, researchers determine protein structures experimentally by X-ray crystallography and nuclear magnetic resonance (NMR), both laborious processes.

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