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Article: Pharmacology and preclinical pharmacokinetics of peppermint oil.
- Article from:
- Phytomedicine: International Journal of Phytotherapy & Phytopharmacology
- Article date:
- August 1, 2005
- Author:
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Copyright informationCOPYRIGHT 2005 Urban & Fischer Verlag. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Abstract
The principal pharmacodynamic effect of peppermint oil relevant to the gastrointestinal tract is a dose-related antispasmodic effect on the smooth musculature due to the interference of menthol with the movement of calcium across the cell membrane. The choleretic and antifoaming effects of peppermint oil may play an additional role in medicinal use.
Peppermint oil is relatively rapidly absorbed after oral administration and eliminated mainly via the bile. The major biliary metabolite is menthol glucuronide, which undergoes enterohepatic circulation. The urinary metabolites result from hydroxylation at the C-7 methyl group at C-8 and C-9 of the isopropyl ...
Related newspaper, magazine, and journal articles:
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Article: REFINED PEPPERMINT OIL EXPORTATION TO BE PROTECTED
AsiaInfo Services;
December 30, 1996 ;
122 words
...AsiaInfo Services 12-30-1996 Refined Peppermint Oil Exportation to be Protected CHINA...recent survey shows that China's refined peppermint oil exportation market has been gradually...in 1995, while the volume of refined peppermint oil from India put into American market...
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