Article: Vitamin C prevents pregnancy complication.(supplementing research)(Brief Article)

One hundred-nine pregnant women living in Mexico City who were not taking vitamin supplements were randomly assigned to receive, in double-blind fashion, 100 mg/day of vitamin C or placebo. Treatment was begun in the 20th week of gestation. The mean dietary vitamin C intakes were 63 and 68 mg/day in the placebo and vitamin C groups, respectively. The incidence of premature rupture of the chorioamniotic membranes (PROM) was 24.6% in the placebo group and 7.7% in the vitamin C group (relative risk = 0.26; 95% confidence interval, 0.078-0.837).

Comment: PROM affects 10-20% of all pregnancies. It is the main known cause of preterm delivery and is associated with ...

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