Article: Methicillin-resistant Staphylococcus aureus skin infections.(Letter to the Editor)

To the Editor: Moran et al. write, "In areas with a high prevalence of CA-MRSA [community acquired methicillin-resistant Staphylococcus aureus], empiric treatment for skin and soft tissue infections (SSTIs) with [beta]-lactam agents such as cephalexin may no longer be appropriate. Oral agents such as clindamycin or trimethoprim/sul famethoxazole and rifampin should be considered in CA-MRSA" (1). However, some studies have had different results. Lee et al. reported that 31 (84%) of 37 Texas children with CA-MRSA SSTIs showed clinical improvement after incision and drainage, even though they received an "ineffective" antimicrobial agent that was not changed after the ...

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