Article: Lyme without erythema migrans is not so rare.(Infectious Diseases)(Brief Article)

SNOWMASS, COLO. -- Lyme disease patients without erythema migrans were thought to be rare--until they showed up frequently in a large trial of the Lyme disease vaccine, Linda K. Bockenstedt, M.D., said at a symposium sponsored by the American College of Rheumatology.

In that trial, 269 cases of Lyme disease were detected by serum assay, of which 42, or about 16%, involved patients without erythema migrans. However, those patients did have flulike symptoms, such as malaise, fever, myalgia, migratory arthralgias, occipital headache, and neck stiffness. They did not have any upper respiratory symptoms, such as cough.

Additionally, Dr. Bockenstedt, of the ...

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