Article: Dynavax's TOLAMBA(TM) Demonstrates Safety in Phase 1 Trial of Ragweed Allergic Children.

Presentation at ACAAI Confirms Same High Dose Level Can Be Used in Both Adults and Children

BERKELEY, Calif., Nov. 7 /PRNewswire-FirstCall/ -- Dynavax Technologies Corporation announced presentation of data from a Phase 1 trial of its ragweed allergy immunotherapy, TOLAMBA, demonstrating that it was safe to test further in ragweed allergic children at a dose level equivalent to the regimen used in adults. TOLAMBA is currently being evaluated in two large- scale clinical trials. A two-year Phase 2/3 trial in adults is anticipated to yield data in the first quarter of 2006. A trial in 313 ragweed allergic children, designed to be supportive of the company's ...

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