Article: Hydroxychloroquine vs. clobetasol rinse to treat oral lichen planus.(CLINICAL TRIAL REVIEW)

This study is currently recruiting patients. Sponsored by National Institute of Dental and Craniofacial Research (NIDCR). This study will compare 2 treatments for oral lichen planus: hydroxychloroquine (Plaquenil) tablets and clobetasol oral rinse. Oral lichen planus is a chronic disorder in which patients have painful mouth ulcers that interfere with meals and daily functioning. It is most commonly treated with topical or systemic corticosteroids, but these drugs have a number of side effects, most commonly yeast infection, and chronic systemic use of them can lead to diabetes, osteoporosis, weight gain, and other complications. ...

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