Article: Exelixis, Wyeth Enter $158M Agreement For FXR Program.

Byline: Karen Pihl-Carey, Staff Writer

Barely two weeks after inking a deal with Bristol-Myers Squibb Co. for liver X receptor (LXR) agonists, Exelixis Inc. signed a similar agreement with Wyeth Pharmaceuticals - this time for compounds that target the farnesoid X receptor (FXR).

South San Francisco-based Exelixis now has major pharmaceutical companies advancing two of the three main preclinical programs acquired in September 2004 through the buyout of San Diego-based X-Ceptor Therapeutics Inc. for $22.3 million. (See BioWorld Today, Sept. 29, 2004.)

Exelixis has already made back that money with the up-front payments from BMS and Wyeth.

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