Article: Commentary--improving diabetes care by combating clinical inertia.

Over the last 10 years, numerous clinical trials have provided consistent and strong evidence that adequate control of glycated hemoglobin (HbA1c), blood pressure (BP), and LDL-cholesterol (LDL) levels significantly reduces major macrovascular complications (Pyorala et al. 1997; Hansson et al. 1998), microvascular complications (U.K. Prospective Diabetes Study [UKPDS] Group 1998), and mortality in adults with type 2 diabetes mellitus. Clinical strategies that simultaneously control HbA1c, BP, and LDL may yield multiplicative benefits. For example, in one multifactorial diabetes clinical trial, simultaneous intensification of care across multiple clinical domains reduced ...

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