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Article: Saga of Wilms' tumor: Lessons learnt from the past.(Review Articles)
- Article from:
- Journal of Indian Association of Pediatric Surgeons
- Article date:
- October 1, 2005
- Author:
CopyrightCOPYRIGHT 2005 Medknow Publications Pvt. Ltd. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Byline: Devendra. Gupta, Shilpa. Sharma, Sandeep. Agarwala, Robert. Carachi
Wilms' tumor (WT) represents 6% of childhood cancers. Recent advances in molecular biology have significant implications for the clinical management. A dramatic improvement in overall cure has resulted from the adoption of multimodality treatment during the past few decades. National Wilms' Tumor Study (NWTS), and the Societe Internationale d'Oncologie Pediatrique (SIOP) have laid down the guidelines for standardized treatment of WT, though differing in the diagnostic and therapeutic approach. Both these groups currently aim at intensifying treatment for patients with poor prognosticators ...