Article: Dynavax's Ragweed Allergy Therapy, TOLAMBA(TM), Achieves Primary Efficacy and Safety Endpoints in Phase 2/3 Trial.

Statistical Significance Achieved in Primary Endpoint (p=0.024) and Major Secondary Endpoints; Pivotal Phase 3 Trial Anticipated to Begin First Half of 2006

BERKELEY, Calif., Jan. 18 /PRNewswire-FirstCall/ -- Dynavax Technologies Corporation announced that results from a two-year Phase 2/3 clinical trial of TOLAMBA, a ragweed allergy immunotherapeutic, showed that patients treated with TOLAMBA experienced a statistically significant reduction in total nasal symptom scores (TNSS) compared to placebo-treated patients in the second year of the trial, the primary efficacy endpoint of the study (p=0.024). Results also showed significant clinical benefit relative to ...

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