|
|
Article: Hydrolysis of aryl hydrogen maleate esters mediated by cyclodextrins--effect on the intramolecular catalysis (1).
- Article from:
- Canadian Journal of Chemistry
- Article date:
- September 1, 2005
- Author:
CopyrightCOPYRIGHT 2005 NRC Research Press. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
|
Introduction
Intramolecular catalysis has been used as a model system because it gives important information about enzyme mechanisms (1-3). These reactions are very much dependent on the relative position of the reacting groups and the time that they remain at the proper distance for reaction (4).
Cyclodextrins (CD), which are cyclic oligomers of [alpha]-D-glucopyranose, have a well-defined cavity (5). They form inclusion complexes with a wide variety of species in aqueous solution (6, 7), and this effect has resulted in multiple industrial applications (8, 9). As a result of the host--guest interaction between the organic substrate and the ...