Article: Insomnia curbs antidepressant response in aged.(Psychiatry)

DENVER -- Chronic insomnia in depressed elderly patients confers roughly a ninefold increased risk of continued depression after as much as 12 months of antidepressant therapy, Wilfred Pigeon, Ph.D., reported at the annual meeting of the Associated Professional Sleep Societies.

"These findings suggest that chronic insomnia blunts treatment response in patients in this intervention study. This means, therefore, that chronic insomnia is not only a precipitating factor, as has been shown by a dozen or so studies, but that it now can also be considered a perpetuating factor, at least in this elderly sample. As such, it represents a modifiable risk factor for ...

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