Article: Melatonin for cancer.(benefits of melatonin)

The indolamine hormone melatonin, secreted by the pineal gland, is widely acknowledged for its effects on sleep and circadian rhythm, and is used by many people as a sleep aid and to prevent jet lag. Less widely known are its antiproliferative, oncostatic, antioxidant, and immunostimulatory effects, which could prove beneficial in cancer treatment.

Potential mechanisms of action that have been proposed include downregulation of oncogene expression, inhibition of growth factors, suppression of linoleic acid uptake by tumor cells, and antiangiogenic effects. Melatonin also modulates the cytostatic and cytotoxic effects of chemotherapeutic agents (J. Clin. Oncol. ...

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