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Article: Paget's patients develop resistance to pamidronate.(Metabolic Disorders)
- Article from:
- Family Practice News
- Article date:
- March 15, 2006
- Author:
CopyrightCOPYRIGHT 2006 International Medical News Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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FORT LAUDERDALE, FLA. -- Reduced responsiveness to repeat bisphosphonate treatment in patients with Paget's disease of bone appears to be limited to pamidronate and may not be a problem with the newer, more potent agents, Dr. Socrates Papapoulos said at a meeting sponsored by the Paget Foundation for Paget's Disease of Bone and Related Disorders.
"The issue of bisphosphonate resistance does not appear to be of primary importance for our clinical practice, especially with the more potent agents now available," said Dr. Papapoulos, professor of medicine and director of bone and mineral research at Leiden (the Netherlands) University Medical Center.
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