Article: Trends in antibiotic resistance of corneal pathogens: Part I. An analysis of commonly used ocular antibiotics.(Original Article)(Clinical report)

Byline: Savitri. Sharma, Derek. Kunimoto, Prashant. Garg, Gullapalli. Rao

Purpose: To analyse commonly used ocular antibiotics and determine their in-vitro efficacies against bacterial keratitis pathogens. Methods: A retrospective review of microbiology records at the LV Prasad Eye Institute in Hyderabad, India identified 1,633 bacterial keratitis isolates. Antibiotic susceptibility of corneal isolates was determined for various ocular antibiotics using the Kirby-Bauer disc-diffusion method. Results: Cefazolin had coverage against 1,296 (83.0%) of 1,562 isolates tested; chloramphenicol against 1,136 (71.7%) of 1,585 isolates; ciprofloxacin against 1,080 (69.3%) ...

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