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Article: Growth factors in corneal epithelial wound healing.(Letter To Editor)(Letter to the editor)
- Article from:
- Indian Journal of Ophthalmology
- Article date:
- April 1, 2003
- Author:
CopyrightCOPYRIGHT 2003 Medknow Publications Pvt. Ltd. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Byline: Nitin. Mukerji, Namrata. Sharma, Rasik. Vajpayee
Dear Editor,
Agrawal and Tsai[1] have adequately addressed the role of cytokines and growth factors in corneal epithelial regeneration. However, the role of a few more growth factors in addition to the ones mentioned viz. EGF, HGF, KGF and TGF-[1] needs to be highlighted.
Fibroblast growth factor (FGF) [2]:
Both acidic and basic FGF (aFGF and bFGF) have a mitogenic effect on the corneal epithelium resulting in faster re-epithelisation; the effect being dose- responsive. aFGF is more potent than bFGF, probably due to variation in corneal sensitivity or a difference in the ...