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Article: Combined Use of ATACAND(R) (candesartan cilexetil) and ACE Inhibitor Improves Heart Failure Outcomes More Than ACE Inhibitor Alone.

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PR Newswire
Article date:
May 4, 2006
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- American Heart Journal Publishes Analysis of Landmark CHARM-Added Trial -

WILMINGTON, Del., May 4 /PRNewswire-FirstCall/ -- AstraZeneca today announced the publication of a supplemental analysis from the Candesartan in Heart failure: Assessment of Reduction in Mortality and Morbidity (CHARM)-Added trial in the May issue of the American Heart Journal. This analysis provides evidence that the clinical benefits of ATACAND in reducing the risk of cardiovascular death and heart failure hospitalizations in patients with symptomatic heart failure and reduced heart pump function were not modified by baseline dose of ACE inhibitor, beta-blocker use at baseline, or ACE ...

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