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Article: Does vitamin B12 help prevent cardiovascular disease?(Literature Review & Commentary)
- Article from:
- Townsend Letter: The Examiner of Alternative Medicine
- Article date:
- May 1, 2006
- Author:
CopyrightCOPYRIGHT 2006 The Townsend Letter Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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The Vitamin Intervention for Stroke Prevention (VISP) trial did not show efficacy of high-dose vitamin therapy (2.5 mg of folic acid, 25 mg of pyridoxine, and 400 mcg of vitamin B12 daily) as compared with low-dose vitamin therapy (20 mcg of folic acid, 200 mcg of vitamin B6, and 6 mcg of vitamin B12 daily) with respect to recurrent vascular events in patients with a history of a stroke.
In a new study, the data from the VISP trial were re-analyzed, after exclusion of patients with low and very high vitamin B12 levels at baseline (
<250 and>637 pmol/L, representing the 25th and 95th percentiles). Patients with very low vitamin B12 levels (
Comment: The results of this ...