Article: Preliminary Results from a Phase IIIb Study Showed Patients With Wet AMD Treated With Lucentis Quarterly Experienced a 16-Letter Benefit Over the Control Group at One Year.

Lucentis Groups Showed Initial Increase in Vision from Baseline With Monthly Dosing and Returned to Baseline With Quarterly Treatments

SOUTH SAN FRANCISCO, Calif., June 2 /PRNewswire-FirstCall/ -- Genentech, Inc. announced today that a Phase IIIb clinical study of a quarterly dosing regimen of the investigational drug Lucentis(TM) (ranibizumab) for the treatment of wet age-related macular degeneration (AMD) met its primary efficacy endpoint by preventing vision loss as measured by mean change in visual acuity from baseline to month 12. In this study, called PIER, patients receive Lucentis (0.3 mg or 0.5 mg respectively) or sham injections once per month for the ...






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