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Article: Gum copal and gum damar: Novel matrix forming materials for sustained drug delivery.(Research Paper)
- Article from:
- Indian Journal of Pharmaceutical Sciences
- Article date:
- January 1, 2006
- Author:
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Byline: D. Morkhade, S. Fulzele, P. Satturwar, S. Joshi
This study concerns the evaluation of natural gum copal and gum damar as novel sustained release matrix forming materials in tablet formulation. Along with the physicochemical properties, gum copal and gum damar were characterized for molecular weight, polydispersity index and glass transition temperature. Matrix tablets were prepared by wet granulation technique using isopropyl alcohol as a granulating agent. Diclofenac sodium was used as a model drug. Tablet weight (250 mg) and diameter (9 mm) was kept constant. Tablets were evaluated for pharmacotechnical properties, drug content uniformity and in vitro ...