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Article: Topical 5% 5-fluorouracil cream in the treatment of plantar warts: a prospective, randomized, and controlled clinical study.
- Article from:
- Journal of Drugs in Dermatology
- Article date:
- May 1, 2006
- Author:
CopyrightCOPYRIGHT 2006 Journal of Drugs in Dermatology, Inc. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Abstract
Topical 5-fluorouracil (5-FU) is an antineoplastic antimetabolite that inhibits DNA and RNA synthesis, thereby preventing cell replication and proliferation. This mechanism of action may allow topical 5-FU to be utilized in the treatment of human papilloma virus (HPV). We conducted a study comparing 5% 5-FU cream under tape occlusion versus tape occlusion alone in 40 patients presenting with plantar warts. Nineteen out of 20 patients (95%) randomized to 5% 5-FU with tape occlusion had complete eradication of all plantar warts within 12 weeks of treatment. The average time to cure occurred at 9 weeks of treatment. Three patients (15%) had a recurrence at ...
Related newspaper, magazine, and journal articles:
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Plantar Warts.
Clinical Reference Systems;
July 1, 1999 ;
687 words
... ... treated? There are various ways to treat plantar warts. However, the warts are sometimes ... How long will the effects last? Most plantar warts go away without treatment in 6 months ... plantar wart. What can I do to prevent plantar warts? Plantar warts may occur more ...
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